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Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of t...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Macedo, Bruno, Cordeiro, Yraima
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454936/
https://ncbi.nlm.nih.gov/pubmed/28513534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051023
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