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Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of t...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Macedo, Bruno, Cordeiro, Yraima
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454936/
https://ncbi.nlm.nih.gov/pubmed/28513534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051023
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