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Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria

BACKGROUND: An increasing number of proteins are being shown to assemble into amyloid structures that lead to pathological states. Among them, mammalian prions outstand due to their ability to transmit the pathogenic conformation, becoming thus infectious. The structural conversion of the cellular p...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Macedo, Bruno, Sant’Anna, Ricardo, Navarro, Susanna, Cordeiro, Yraima, Ventura, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634817/
https://ncbi.nlm.nih.gov/pubmed/26536866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0361-y
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