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Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria

BACKGROUND: An increasing number of proteins are being shown to assemble into amyloid structures that lead to pathological states. Among them, mammalian prions outstand due to their ability to transmit the pathogenic conformation, becoming thus infectious. The structural conversion of the cellular p...

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書目詳細資料
發表在:Microb Cell Fact
Main Authors: Macedo, Bruno, Sant’Anna, Ricardo, Navarro, Susanna, Cordeiro, Yraima, Ventura, Salvador
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634817/
https://ncbi.nlm.nih.gov/pubmed/26536866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0361-y
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