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Mammalian prion amyloid formation in bacteria
Mammalian prion proteins (PrPs) that cause transmissible spongiform encephalopathies are misfolded conformations of the host cellular PrP. The misfolded form, the scrapie PrP (PrP(Sc)), can aggregate into amyloid fibrils that progressively accumulate in the brain, evolving to a pathological phenotyp...
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| Published in: | Prion |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981191/ https://ncbi.nlm.nih.gov/pubmed/26910379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2016.1141859 |
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