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Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of t...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Macedo, Bruno, Cordeiro, Yraima
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454936/
https://ncbi.nlm.nih.gov/pubmed/28513534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051023
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