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Prion protein PrP nucleic acid binding and mobilization implicates retroelements as the replicative component of transmissible spongiform encephalopathy
The existence of more than 30 strains of transmissible spongiform encephalopathy (TSE) and the paucity of infectivity of purified PrP(Sc), as well as considerations of PrP structure, are inconsistent with the protein-only (prion) theory of TSE. Nucleic acid is a strong contender as a second componen...
Gardado en:
| Publicado en: | Arch Virol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer Vienna
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7024060/ https://ncbi.nlm.nih.gov/pubmed/32025859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-020-04529-2 |
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