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Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties
The agents responsible for transmissible spongiform encephalopathies (TSEs), or prion diseases, contain as a major component PrP(Sc), an abnormal conformer of the host glycoprotein PrP(C). TSE agents are distinguished by differences in phenotypic properties in the host, which nevertheless can contai...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
European Molecular Biology Organization
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590993/ https://ncbi.nlm.nih.gov/pubmed/23395905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.6 |
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