Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties

The agents responsible for transmissible spongiform encephalopathies (TSEs), or prion diseases, contain as a major component PrP(Sc), an abnormal conformer of the host glycoprotein PrP(C). TSE agents are distinguished by differences in phenotypic properties in the host, which nevertheless can contai...

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Detalhes bibliográficos
Main Authors: Cancellotti, Enrico, Mahal, Sukhvir P, Somerville, Robert, Diack, Abigail, Brown, Deborah, Piccardo, Pedro, Weissmann, Charles, Manson, Jean C
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590993/
https://ncbi.nlm.nih.gov/pubmed/23395905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.6
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