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Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies
The misfolding of the cellular prion protein (PrP(C)) into the disease-associated isoform (PrP(Sc)) and its accumulation as amyloid fibrils in the central nervous system is one of the central events in transmissible spongiform encephalopathies (TSEs). Due to the proteinaceous nature of the causal ag...
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| Publicado no: | Pathogens |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5750591/ https://ncbi.nlm.nih.gov/pubmed/29240682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens6040067 |
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