Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies

The misfolding of the cellular prion protein (PrP(C)) into the disease-associated isoform (PrP(Sc)) and its accumulation as amyloid fibrils in the central nervous system is one of the central events in transmissible spongiform encephalopathies (TSEs). Due to the proteinaceous nature of the causal ag...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pathogens
Egile Nagusiak: Charco, Jorge M., Eraña, Hasier, Venegas, Vanessa, García-Martínez, Sandra, López-Moreno, Rafael, González-Miranda, Ezequiel, Pérez-Castro, Miguel Ángel, Castilla, Joaquín
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Review
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750591/
https://ncbi.nlm.nih.gov/pubmed/29240682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens6040067
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