Glycosylation of PrP(C) Determines Timing of Neuroinvasion and Targeting in the Brain following Transmissible Spongiform Encephalopathy Infection by a Peripheral Route

Transmissible spongiform encephalopathy (TSE) infectivity naturally spreads from site of entry in the periphery to the central nervous system where pathological lesions are formed. Several routes and cells within the host have been identified as important for facilitating the infectious process. Exp...

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Main Authors: Cancellotti, Enrico, Bradford, Barry M., Tuzi, Nadia L., Hickey, Raymond D., Brown, Debbie, Brown, Karen L., Barron, Rona M., Kisielewski, Dorothy, Piccardo, Pedro, Manson, Jean C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838100/
https://ncbi.nlm.nih.gov/pubmed/20106922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02374-09
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