Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response

Mutations in the Epidermal growth factor receptor (EGFR) kinase domain, such as the L858R missense mutation and deletions spanning the conserved sequence (747)LREA(750), are sensitive to tyrosine kinase inhibitors (TKIs). The gatekeeper site residue mutation, T790M accounts for around 60% of acquire...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Proteomics
Asıl Yazarlar: Zhang, Xu, Maity, Tapan, Kashyap, Manoj K., Bansal, Mukesh, Venugopalan, Abhilash, Singh, Sahib, Awasthi, Shivangi, Marimuthu, Arivusudar, Charles Jacob, Harrys Kishore, Belkina, Natalya, Pitts, Stephanie, Cultraro, Constance M., Gao, Shaojian, Kirkali, Guldal, Biswas, Romi, Chaerkady, Raghothama, Califano, Andrea, Pandey, Akhilesh, Guha, Udayan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2017
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417828/
https://ncbi.nlm.nih.gov/pubmed/28331001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M117.067439
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