Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS

We have used unbiased phosphoproteomic approaches, based on quantitative mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC), to identify tyrosine phosphorylated proteins in isogenic human bronchial epithelial cells (HBECs) and human lung adenocarcinoma cell line...

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Autori principali: Guha, Udayan, Chaerkady, Raghothama, Marimuthu, Arivusudar, Patterson, A. Scott, Kashyap, Manoj K., Harsha, H. C., Sato, Mitsuo, Bader, Joel S., Lash, Alex E., Minna, John D., Pandey, Akhilesh, Varmus, Harold E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531065/
https://ncbi.nlm.nih.gov/pubmed/18776048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806158105
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