Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V

Lung cancer is the leading cause of cancer death in both men and women. Tumor heterogeneity is an impediment to targeted treatment of all cancers, including lung cancer. Here, we sought to characterize tumor proteome and phosphoproteome changes by longitudinal, prospective collection of tumor tissue...

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Bibliografiska uppgifter
I publikationen:Mol Cell Proteomics
Huvudupphovsmän: Zhang, Xu, Nguyen, Khoa Dang, Rudnick, Paul A., Roper, Nitin, Kawaler, Emily, Maity, Tapan K., Awasthi, Shivangi, Gao, Shaojian, Biswas, Romi, Venugopalan, Abhilash, Cultraro, Constance M., Fenyö, David, Guha, Udayan
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442362/
https://ncbi.nlm.nih.gov/pubmed/30617155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.001266
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