Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V

Lung cancer is the leading cause of cancer death in both men and women. Tumor heterogeneity is an impediment to targeted treatment of all cancers, including lung cancer. Here, we sought to characterize tumor proteome and phosphoproteome changes by longitudinal, prospective collection of tumor tissue...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Zhang, Xu, Nguyen, Khoa Dang, Rudnick, Paul A., Roper, Nitin, Kawaler, Emily, Maity, Tapan K., Awasthi, Shivangi, Gao, Shaojian, Biswas, Romi, Venugopalan, Abhilash, Cultraro, Constance M., Fenyö, David, Guha, Udayan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442362/
https://ncbi.nlm.nih.gov/pubmed/30617155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.001266
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