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Identifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics
Mutations in the Epidermal growth factor receptor (EGFR) kinase domain occur in 10–30% of lung adenocarcinoma and are associated with tyrosine kinase inhibitor (TKI) sensitivity. We sought to identify the immediate direct and indirect phosphorylation targets of mutant EGFRs in lung adenocarcinoma. W...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Proteomics |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461560/ https://ncbi.nlm.nih.gov/pubmed/25404012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400315 |
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