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Identifying novel targets of oncogenic EGF receptor signaling in lung cancer through global phosphoproteomics
Mutations in the Epidermal growth factor receptor (EGFR) kinase domain occur in 10–30% of lung adenocarcinoma and are associated with tyrosine kinase inhibitor (TKI) sensitivity. We sought to identify the immediate direct and indirect phosphorylation targets of mutant EGFRs in lung adenocarcinoma. W...
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| Опубликовано в: : | Proteomics |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461560/ https://ncbi.nlm.nih.gov/pubmed/25404012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400315 |
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