Quantitative Mass Spectrometry to Interrogate Proteomic Heterogeneity in Metastatic Lung Adenocarcinoma and Validate a Novel Somatic Mutation CDK12-G879V

Lung cancer is the leading cause of cancer death in both men and women. Tumor heterogeneity is an impediment to targeted treatment of all cancers, including lung cancer. Here, we sought to characterize tumor proteome and phosphoproteome changes by longitudinal, prospective collection of tumor tissue...

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Библиографические подробности
Опубликовано в: :Mol Cell Proteomics
Главные авторы: Zhang, Xu, Nguyen, Khoa Dang, Rudnick, Paul A., Roper, Nitin, Kawaler, Emily, Maity, Tapan K., Awasthi, Shivangi, Gao, Shaojian, Biswas, Romi, Venugopalan, Abhilash, Cultraro, Constance M., Fenyö, David, Guha, Udayan
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2019
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442362/
https://ncbi.nlm.nih.gov/pubmed/30617155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.001266
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