Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition

Accumulation and deposition of amyloid-β (Aβ) in the brain represent an early and perhaps necessary step in the pathogenesis of Alzheimer's disease (AD). Aβ accumulation leads to the formation of Aβ aggregates, which may directly and indirectly lead to eventual neurodegeneration. While Aβ produ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Liu, Chia-Chen, Hu, Jin, Zhao, Na, Wang, Jian, Wang, Na, Cirrito, John R., Kanekiyo, Takahisa, Holtzman, David M., Bu, Guojun
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2017
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391682/
https://ncbi.nlm.nih.gov/pubmed/28275161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3442-16.2017
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares