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Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition
Accumulation and deposition of amyloid-β (Aβ) in the brain represent an early and perhaps necessary step in the pathogenesis of Alzheimer's disease (AD). Aβ accumulation leads to the formation of Aβ aggregates, which may directly and indirectly lead to eventual neurodegeneration. While Aβ produ...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391682/ https://ncbi.nlm.nih.gov/pubmed/28275161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3442-16.2017 |
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