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The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

Accumulation and aggregation of amyloid-β (Aβ) peptides in the brain trigger the development of progressive neurodegeneration and dementia associated with Alzheimer’s disease (AD). Perturbation in Aβ clearance, rather than Aβ production, is likely the cause of sporadic, late-onset AD, which accounts...

詳細記述

保存先:
書誌詳細
主要な著者: Kanekiyo, Takahisa, Bu, Guojun
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033011/
https://ncbi.nlm.nih.gov/pubmed/24904407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00093
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