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The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

Accumulation and aggregation of amyloid-β (Aβ) peptides in the brain trigger the development of progressive neurodegeneration and dementia associated with Alzheimer’s disease (AD). Perturbation in Aβ clearance, rather than Aβ production, is likely the cause of sporadic, late-onset AD, which accounts...

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Sonraí Bibleagrafaíochta
Main Authors: Kanekiyo, Takahisa, Bu, Guojun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033011/
https://ncbi.nlm.nih.gov/pubmed/24904407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00093
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