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Low Density Lipoprotein Receptor-related Protein 1 Promotes Anti-apoptotic Signaling in Neurons by Activating Akt Survival Pathway

The low density lipoprotein receptor-related protein 1 (LRP1) is a multi-ligand receptor abundantly expressed in neurons. Previous work has shown that brain LRP1 levels are decreased during aging and in Alzheimer disease. Although mounting evidence has demonstrated a role for LRP1 in the metabolism...

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Detalhes bibliográficos
Main Authors: Fuentealba, Rodrigo A., Liu, Qiang, Kanekiyo, Takahisa, Zhang, Juan, Bu, Guojun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797175/
https://ncbi.nlm.nih.gov/pubmed/19815552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021030
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