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The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease

Accumulation and aggregation of amyloid-β (Aβ) peptides in the brain trigger the development of progressive neurodegeneration and dementia associated with Alzheimer’s disease (AD). Perturbation in Aβ clearance, rather than Aβ production, is likely the cause of sporadic, late-onset AD, which accounts...

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Detaylı Bibliyografya
Asıl Yazarlar: Kanekiyo, Takahisa, Bu, Guojun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033011/
https://ncbi.nlm.nih.gov/pubmed/24904407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00093
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