LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-β

Impaired clearance of amyloid-β (Aβ) is a major pathogenic event for Alzheimer's disease (AD). Aβ depositions in brain parenchyma as senile plaques and along cerebrovasculature as cerebral amyloid angiopathy (CAA) are hallmarks of AD. A major pathway that mediates brain Aβ clearance is the cere...

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Detaylı Bibliyografya
Asıl Yazarlar: Kanekiyo, Takahisa, Liu, Chia-Chen, Shinohara, Mitsuru, Li, Jie, Bu, Guojun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508699/
https://ncbi.nlm.nih.gov/pubmed/23152628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3987-12.2012
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