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Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggressive features of esophageal squamous carcinoma. It was foun...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Li, Yaqing, Li, Xiaoran, Kan, Quancheng, Zhang, Mingzhi, Li, Xiaoli, Xu, Ruiping, Wang, Junsheng, Yu, Dandan, Goscinski, Mariusz Adam, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352034/
https://ncbi.nlm.nih.gov/pubmed/27911865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13717
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