Decreased expression of pyruvate dehydrogenase A1 predicts an unfavorable prognosis in ovarian carcinoma

Pyruvate dehydrogenase A1 (PDHA1) serves as a gate-keeper enzyme link between glycolysis and the mitochondrial citric acid cycle. The inhibition of PDHA1 in cancer cells can result in an increased Warburg effect and a more aggressive phenotype in cancer cells. This study was conducted to investigate...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Li, Yaqing, Huang, Ruixia, Li, Xiaoli, Li, Xiaoran, Yu, Dandan, Zhang, Mingzhi, Wen, Jianguo, Goscinski, Mariusz Adam, Trope, Claes G, Nesland, Jahn M, Suo, Zhenhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043116/
https://ncbi.nlm.nih.gov/pubmed/27725912
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