Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers

Cells generate adenosine-5′-triphosphate (ATP), the major currency for energy-consuming reactions, through mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. One of the remarkable features of cancer cells is aerobic glycolysis, also known as the “Warburg Effect”, in which cancer cells...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zhong, Yali, Li, Xiaoli, Ji, Yasai, Li, Xiaoran, Li, Yaqing, Yu, Dandan, Yuan, Yuan, Liu, Jian, Li, Huixiang, Zhang, Mingzhi, Ji, Zhenyu, Fan, Dandan, Wen, Jianguo, Goscinski, Mariusz Adam, Yuan, Long, Hao, Bin, Nesland, Jahn M, Suo, Zhenhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355102/
https://ncbi.nlm.nih.gov/pubmed/28076853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14527
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