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Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers
Cells generate adenosine-5′-triphosphate (ATP), the major currency for energy-consuming reactions, through mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. One of the remarkable features of cancer cells is aerobic glycolysis, also known as the “Warburg Effect”, in which cancer cells...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355102/ https://ncbi.nlm.nih.gov/pubmed/28076853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14527 |
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