Application of mitochondrial pyruvate carrier blocker UK5099 creates metabolic reprogram and greater stem-like properties in LnCap prostate cancer cells in vitro

Aerobic glycolysis is one of the important hallmarks of cancer cells and eukaryotic cells. In this study, we have investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with UK5099 and the metabolic alteration as well as stemness phenotype of prostatic cancer cells. It w...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhong, Yali, Li, Xiaoran, Yu, Dandan, Li, Xiaoli, Li, Yaqing, Long, Yuan, Yuan, Yuan, Ji, Zhenyu, Zhang, Mingzhi, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741963/
https://ncbi.nlm.nih.gov/pubmed/26413751
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