Application of mitochondrial pyruvate carrier blocker UK5099 creates metabolic reprogram and greater stem-like properties in LnCap prostate cancer cells in vitro

Aerobic glycolysis is one of the important hallmarks of cancer cells and eukaryotic cells. In this study, we have investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with UK5099 and the metabolic alteration as well as stemness phenotype of prostatic cancer cells. It w...

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Vydáno v:Oncotarget
Hlavní autoři: Zhong, Yali, Li, Xiaoran, Yu, Dandan, Li, Xiaoli, Li, Yaqing, Long, Yuan, Yuan, Yuan, Ji, Zhenyu, Zhang, Mingzhi, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741963/
https://ncbi.nlm.nih.gov/pubmed/26413751
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