Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggressive features of esophageal squamous carcinoma. It was foun...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Li, Yaqing, Li, Xiaoran, Kan, Quancheng, Zhang, Mingzhi, Li, Xiaoli, Xu, Ruiping, Wang, Junsheng, Yu, Dandan, Goscinski, Mariusz Adam, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352034/
https://ncbi.nlm.nih.gov/pubmed/27911865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13717
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