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Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggressive features of esophageal squamous carcinoma. It was foun...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Li, Yaqing, Li, Xiaoran, Kan, Quancheng, Zhang, Mingzhi, Li, Xiaoli, Xu, Ruiping, Wang, Junsheng, Yu, Dandan, Goscinski, Mariusz Adam, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352034/
https://ncbi.nlm.nih.gov/pubmed/27911865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13717
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