Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells

One of the remarkable features of cancer cells is aerobic glycolysis, a phenomenon known as the “Warburg Effect”, in which cells rely preferentially on glycolysis instead of oxidative phosphorylation (OXPHOS) as the main energy source even in the presence of high oxygen tension. Cells with dysfuncti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xiaoli, Han, Gaoyang, Li, Xiaoran, Kan, Quancheng, Fan, Zhirui, Li, Yaqing, Ji, Yasai, Zhao, Jing, Zhang, Mingzhi, Grigalavicius, Mantas, Berge, Viktor, Goscinski, Mariusz Adam, M. Nesland, Jahn, Suo, Zhenhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542273/
https://ncbi.nlm.nih.gov/pubmed/28624784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18199
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