Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells

One of the remarkable features of cancer cells is aerobic glycolysis, a phenomenon known as the “Warburg Effect”, in which cells rely preferentially on glycolysis instead of oxidative phosphorylation (OXPHOS) as the main energy source even in the presence of high oxygen tension. Cells with dysfuncti...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Li, Xiaoli, Han, Gaoyang, Li, Xiaoran, Kan, Quancheng, Fan, Zhirui, Li, Yaqing, Ji, Yasai, Zhao, Jing, Zhang, Mingzhi, Grigalavicius, Mantas, Berge, Viktor, Goscinski, Mariusz Adam, M. Nesland, Jahn, Suo, Zhenhe
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542273/
https://ncbi.nlm.nih.gov/pubmed/28624784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18199
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