Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane appears to be essential in anabolic and catabolic intermediar...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Xiaoli, Li, Yaqing, Han, Gaoyang, Li, Xiaoran, Ji, Yasai, Fan, Zhirui, Zhong, Yali, Cao, Jing, Zhao, Jing, Mariusz, Goscinski, Zhang, Mingzhi, Wen, Jianguo, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346765/
https://ncbi.nlm.nih.gov/pubmed/27835892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13210
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