Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane appears to be essential in anabolic and catabolic intermediar...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Xiaoli, Li, Yaqing, Han, Gaoyang, Li, Xiaoran, Ji, Yasai, Fan, Zhirui, Zhong, Yali, Cao, Jing, Zhao, Jing, Mariusz, Goscinski, Zhang, Mingzhi, Wen, Jianguo, Nesland, Jahn M., Suo, Zhenhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346765/
https://ncbi.nlm.nih.gov/pubmed/27835892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13210
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