MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer

BACKGROUND: Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role by transporting pyruvate int...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Li, Xiaoli, Ji, Yasai, Han, Gaoyang, Li, Xiaoran, Fan, Zhirui, Li, Yaqing, Zhong, Yali, Cao, Jing, Zhao, Jing, Zhang, Mingzhi, Wen, Jianguo, Goscinski, Mariusz Adam, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112705/
https://ncbi.nlm.nih.gov/pubmed/27852261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2941-6
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