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MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer
BACKGROUND: Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role by transporting pyruvate int...
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| Veröffentlicht in: | BMC Cancer |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5112705/ https://ncbi.nlm.nih.gov/pubmed/27852261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2941-6 |
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