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Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane appears to be essential in anabolic and catabolic intermediar...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Li, Xiaoli, Li, Yaqing, Han, Gaoyang, Li, Xiaoran, Ji, Yasai, Fan, Zhirui, Zhong, Yali, Cao, Jing, Zhao, Jing, Mariusz, Goscinski, Zhang, Mingzhi, Wen, Jianguo, Nesland, Jahn M., Suo, Zhenhe
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346765/
https://ncbi.nlm.nih.gov/pubmed/27835892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13210
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