Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane appears to be essential in anabolic and catabolic intermediar...

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Publicado en:Oncotarget
Autores principales: Li, Xiaoli, Li, Yaqing, Han, Gaoyang, Li, Xiaoran, Ji, Yasai, Fan, Zhirui, Zhong, Yali, Cao, Jing, Zhao, Jing, Mariusz, Goscinski, Zhang, Mingzhi, Wen, Jianguo, Nesland, Jahn M., Suo, Zhenhe
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346765/
https://ncbi.nlm.nih.gov/pubmed/27835892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13210
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