Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses

Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane appears to be essential in anabolic and catabolic intermediar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Li, Xiaoli, Li, Yaqing, Han, Gaoyang, Li, Xiaoran, Ji, Yasai, Fan, Zhirui, Zhong, Yali, Cao, Jing, Zhao, Jing, Mariusz, Goscinski, Zhang, Mingzhi, Wen, Jianguo, Nesland, Jahn M., Suo, Zhenhe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346765/
https://ncbi.nlm.nih.gov/pubmed/27835892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13210
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