Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells

Flavopiridol (FP) is a pan-cyclin dependent kinase inhibitor, which shows strong efficacy in inducing cancer cell apoptosis. Although FP is potent against most cancer cells in vitro, unfortunately it proved less efficacious in clinical trials in various aggressive cancers. To date, the molecular mec...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Li, Xiaoran, Lu, Jie, Kan, Quancheng, Li, Xiaoli, Fan, Qiong, Li, Yaqing, Huang, Ruixia, Slipicevic, Ana, Dong, Hiep Phuc, Eide, Lars, Wang, Junbai, Zhang, Hongquan, Berge, Viktor, Goscinski, Mariusz Adam, Kvalheim, Gunnar, Nesland, Jahn M., Suo, Zhenhe
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506068/
https://ncbi.nlm.nih.gov/pubmed/28698547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05086-6
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы