Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells

One of the remarkable features of cancer cells is aerobic glycolysis, a phenomenon known as the “Warburg Effect”, in which cells rely preferentially on glycolysis instead of oxidative phosphorylation (OXPHOS) as the main energy source even in the presence of high oxygen tension. Cells with dysfuncti...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Li, Xiaoli, Han, Gaoyang, Li, Xiaoran, Kan, Quancheng, Fan, Zhirui, Li, Yaqing, Ji, Yasai, Zhao, Jing, Zhang, Mingzhi, Grigalavicius, Mantas, Berge, Viktor, Goscinski, Mariusz Adam, M. Nesland, Jahn, Suo, Zhenhe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542273/
https://ncbi.nlm.nih.gov/pubmed/28624784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18199
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