Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggressive features of esophageal squamous carcinoma. It was foun...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Yaqing, Li, Xiaoran, Kan, Quancheng, Zhang, Mingzhi, Li, Xiaoli, Xu, Ruiping, Wang, Junsheng, Yu, Dandan, Goscinski, Mariusz Adam, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352034/
https://ncbi.nlm.nih.gov/pubmed/27911865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13717
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