Artemisinins Target GABA(A) Receptor Signaling and Impair α Cell Identity

Type 1 diabetes is characterized by the destruction of pancreatic β cells, and generating new insulin-producing cells from other cell types is a major aim of regenerative medicine. One promising approach is transdifferentiation of developmentally related pancreatic cell types, including glucagon-pro...

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Publicado no:Cell
Main Authors: Li, Jin, Casteels, Tamara, Frogne, Thomas, Ingvorsen, Camilla, Honoré, Christian, Courtney, Monica, Huber, Kilian V.M., Schmitner, Nicole, Kimmel, Robin A., Romanov, Roman A., Sturtzel, Caterina, Lardeau, Charles-Hugues, Klughammer, Johanna, Farlik, Matthias, Sdelci, Sara, Vieira, Andhira, Avolio, Fabio, Briand, François, Baburin, Igor, Májek, Peter, Pauler, Florian M., Penz, Thomas, Stukalov, Alexey, Gridling, Manuela, Parapatics, Katja, Barbieux, Charlotte, Berishvili, Ekaterine, Spittler, Andreas, Colinge, Jacques, Bennett, Keiryn L., Hering, Steffen, Sulpice, Thierry, Bock, Christoph, Distel, Martin, Harkany, Tibor, Meyer, Dirk, Superti-Furga, Giulio, Collombat, Patrick, Hecksher-Sørensen, Jacob, Kubicek, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5236063/
https://ncbi.nlm.nih.gov/pubmed/27916275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.11.010
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