A structure-function approach to optimizing TLR4 ligands for human vaccines

Adjuvants are combined with vaccine antigens to enhance and modify immune responses, and have historically been primarily crude, undefined entities. Introducing toll-like receptor (TLR) ligands has led to a new generation of adjuvants, with TLR4 ligands being the most extensively used in human vacci...

詳細記述

保存先:
書誌詳細
出版年:Clin Transl Immunology
主要な著者: Carter, Darrick, Fox, Christopher B, Day, Tracey A, Guderian, Jeffrey A, Liang, Hong, Rolf, Tom, Vergara, Julie, Sagawa, Zachary K, Ireton, Greg, Orr, Mark T, Desbien, Anthony, Duthie, Malcolm S, Coler, Rhea N, Reed, Steven G
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133366/
https://ncbi.nlm.nih.gov/pubmed/27990284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.63
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