A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7

BACKGROUND: Recent reports that TLR4 and TLR7 ligands can synergistically trigger Th1 biased immune responses suggest that an adjuvant that contains both ligands would be an excellent candidate for co-administration with vaccine antigens for which heavily Th1 biased responses are desired. Ligands of...

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Detalhes bibliográficos
Main Authors: Fox, Christopher B, Sivananthan, Sandra J, Duthie, Malcolm S, Vergara, Julie, Guderian, Jeffrey A, Moon, Elliot, Coblentz, David, Reed, Steven G, Carter, Darrick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014409/
https://ncbi.nlm.nih.gov/pubmed/24766820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-12-17
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