A structure-function approach to optimizing TLR4 ligands for human vaccines

Adjuvants are combined with vaccine antigens to enhance and modify immune responses, and have historically been primarily crude, undefined entities. Introducing toll-like receptor (TLR) ligands has led to a new generation of adjuvants, with TLR4 ligands being the most extensively used in human vacci...

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書目詳細資料
發表在:Clin Transl Immunology
Main Authors: Carter, Darrick, Fox, Christopher B, Day, Tracey A, Guderian, Jeffrey A, Liang, Hong, Rolf, Tom, Vergara, Julie, Sagawa, Zachary K, Ireton, Greg, Orr, Mark T, Desbien, Anthony, Duthie, Malcolm S, Coler, Rhea N, Reed, Steven G
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133366/
https://ncbi.nlm.nih.gov/pubmed/27990284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.63
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