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Use of defined TLR ligands as adjuvants within human vaccines

Our improved understanding of how innate immune responses can be initiated and how they can shape adaptive B- and T-cell responses is having a significant impact on vaccine development by directing the development of defined adjuvants. Experience with first generation vaccines, as well as rapid adva...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Duthie, Malcolm S., Windish, Hillarie Plessner, Fox, Christopher B., Reed, Steven G.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872835/
https://ncbi.nlm.nih.gov/pubmed/21198672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00978.x
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