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IL-18 and subcapsular lymph node macrophages are essential for enhanced B cell responses with TLR4 agonist adjuvants()

Designing modern vaccine adjuvants depends on understanding the cellular and molecular events that connect innate and adaptive immune responses. The synthetic TLR4 agonist GLA formulated in a stable emulsion (GLA-SE) augments both cellular and humoral immune responses to vaccine antigens. This adjuv...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Desbien, Anthony L., Cauwelaert, Natasha Dubois, Reed, Steven J., Bailor, Hilton R., Liang, Hong, Carter, Darrick, Duthie, Malcolm S., Fox, Christopher B., Reed, Steven G., Orr, Mark T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123812/
https://ncbi.nlm.nih.gov/pubmed/27794001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600993
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