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Effective Combination Adjuvants Engage Both TLR and Inflammasome Pathways to Promote Potent Adaptive Immune Responses

The involvement of innate receptors that recognize pathogen and danger associated molecular patterns is critical to programming an effective adaptive immune response to vaccination. The synthetic TLR4 agonist glucopyranosyl lipid adjuvant (GLA) synergizes with the squalene oil-in-water emulsion (SE)...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Seydoux, Emilie, Liang, Hong, Cauwelaert, Natasha Dubois, Archer, Michelle, Rintala, Nicholas D, Kramer, Ryan, Carter, Darrick, Fox, Christopher B, Orr, Mark T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008227/
https://ncbi.nlm.nih.gov/pubmed/29769270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701604
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