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Autoimmune susceptibility imposed by public TCRβ chains

Although the TCR repertoire is highly diverse, a small fraction of TCR chains, referred to as public, preferentially form and are shared by most individuals. Prior studies indicated that public TCRβ may be preferentially deployed in autoimmunity. We hypothesized that if these TCRβ modulate the likel...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhao, Yunqian, Nguyen, Phuong, Vogel, Peter, Li, Bofeng, Jones, Lindsay L., Geiger, Terrence L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116635/
https://ncbi.nlm.nih.gov/pubmed/27869234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37543
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