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Diversification and senescence of Foxp3(+) regulatory T cells during experimental autoimmune encephalomyelitis

The fate of Foxp3(+) regulatory T cells (Treg) responding during autoimmunity is not well defined. We observed a marked elevation in KLRG1(+) CNS-infiltrating Treg in experimental autoimmune encephalomyelitis (EAE), and assessed their origin and properties. KLRG1(+) Treg showed increased activation...

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Detalhes bibliográficos
Main Authors: Tauro, Sharyn, Nguyen, Phuong, Li, Bofeng, Geiger, Terrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775602/
https://ncbi.nlm.nih.gov/pubmed/23436224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242881
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