Modification of the FoxP3 Transcription Factor Principally Affects Inducible T Regulatory Cells in a Model of Experimental Autoimmune Encephalomyelitis

T regulatory (Treg) cells expressing the transcription factor FoxP3 play a key role in protection against autoimmune disease. GFP-FoxP3 reporter mice have been used widely to study the induction, function and stability of both thymically- and peripherally-induced Treg cells. The N-terminal modificat...

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Bibliografiska uppgifter
Huvudupphovsmän: Verhagen, Johan, Burton, Bronwen R., Britton, Graham J., Shepard, Ella R., Anderton, Stephen M., Wraith, David C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620162/
https://ncbi.nlm.nih.gov/pubmed/23593464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061334
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