CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis

A single G protein–coupled receptor (GPCR) can activate multiple signaling cascades based on the binding of different ligands. The biological relevance of this feature in immune regulation has not been evaluated. The chemokine-binding GPCR CXCR3 is preferentially expressed on CD4+ T cells, and canon...

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Detalhes bibliográficos
Main Authors: Zohar, Yaniv, Wildbaum, Gizi, Novak, Rostislav, Salzman, Andrew L., Thelen, Marcus, Alon, Ronen, Barsheshet, Yiftah, Karp, Christopher L., Karin, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001543/
https://ncbi.nlm.nih.gov/pubmed/24713654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71951
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