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Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3(+) regulatory T cells implicates compensatory pathways including regulatory B cells

Oestrogen (17β-oestradiol, E(2)) is a highly effective treatment for experimental autoimmune encephalomyelitis (EAE) that may potentiate Foxp3(+) regulatory T (Treg) cells, which in turn limit the expansion of encephalitogenic T-cell specificities. To determine if Treg cells constitute the major non...

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Bibliografiske detaljer
Main Authors: Subramanian, Sandhya, Yates, Melissa, Vandenbark, Arthur A, Offner, Halina
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044900/
https://ncbi.nlm.nih.gov/pubmed/21091909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03380.x
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