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Oestrogen treatment of experimental autoimmune encephalomyelitis requires 17β-oestradiol-receptor-positive B cells that up-regulate PD-1 on CD4(+) Foxp3(+) regulatory T cells
It is now well accepted that sex hormones have immunoregulatory activity and may prevent exacerbations in multiple sclerosis during pregnancy. Our previous studies demonstrated that oestrogen (17β-oestradiol; E(2)) protection against experimental autoimmune encephalomyelitis (EAE) is mediated mainly...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530084/ https://ncbi.nlm.nih.gov/pubmed/23039230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12013 |
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