Estrogen induces multiple regulatory B cell subtypes and promotes M2 microglia and neuroprotection during experimental autoimmune encephalomyelitis

Sex hormones promote immunoregulatory effects on multiple sclerosis. The current study evaluated estrogen effects on regulatory B cells and resident CNS microglia during experimental autoimmune encephalomyelitis (EAE). Herein, we demonstrate an estrogen-dependent induction of multiple regulatory B c...

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Vydáno v:J Neuroimmunol
Hlavní autoři: Benedek, Gil, Zhang, Jun, Bodhankar, Sheetal, Nguyen, Ha, Kent, Gail, Jordan, Kelley, Manning, Dustin, Vandenbark, Arthur A., Offner, Halina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824954/
https://ncbi.nlm.nih.gov/pubmed/27049561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.02.009
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