PD-1 Interaction with PD-L1 but not PD-L2 on B-cells Mediates Protective Effects of Estrogen against EAE

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of sex steroids such as estrogen and estriol. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cellular basis for E2-induced protection remains uncle...

Full description

Saved in:
Bibliographic Details
Main Authors: Bodhankar, Sheetal, Galipeau, Danielle, Vandenbark, Arthur A, Offner, Halina
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760596/
https://ncbi.nlm.nih.gov/pubmed/24009988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000143
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items