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PD-1 Interaction with PD-L1 but not PD-L2 on B-cells Mediates Protective Effects of Estrogen against EAE

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of sex steroids such as estrogen and estriol. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cellular basis for E2-induced protection remains uncle...

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Detalhes bibliográficos
Main Authors: Bodhankar, Sheetal, Galipeau, Danielle, Vandenbark, Arthur A, Offner, Halina
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760596/
https://ncbi.nlm.nih.gov/pubmed/24009988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000143
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